ABSTRACT
In late December 2019, pneumonia of an unidentified cause was reported in Wuhan, China, and on March 11, 2020, the World Health Organization proclaimed a pandemic of coronavirus disease 2019 (COVID-19). Today, this disease is still infecting millions of people worldwide and is responsible for forcing billions of people to stay under lockdown. This virus posed novel challenges to the research community and had a huge impact on available bioinformatics tools. Hence, the aim of the present chapter is to briefly summarize the role of bioinformatics in COVID-19 research, focusing on publicly available resources such as specific genomic, proteomic, epigenetic, transcriptomic, and toxicogenomic databases and tools for analysis;in vivo and clinical trial databases for COVID-19 drugs;bioinformatics tools and databases for severe acute respiratory syndrome coronavirus 2 drug designing and vaccine developments, resources and tools for clinicians;and mobile apps for tracking the pandemic. © 2023 Elsevier Inc. All rights reserved.